Caroline Sokol, MD, PhD is a physician-scien,st at Massachuse0s General Hospital and
Assistant Professor of Medicine at Harvard Medical School. Her laboratory inves,gates
neuroimmune circuits that govern allergen sensing, allergic immune ini,a,on and itch. Her
research has demonstrated that sensory neurons are primary sensors of protease allergens and
play a central role in ac,va,ng dendri,c cells and ini,a,ng allergic immunity. Her team also
iden,fied a novel neuroimmune circuit in which IL-3-producing γc T cells prime IL-3 receptorexpressing
sensory neurons to respond to minimal allergen exposure, linking microbial and
environmental cues to allergic sensi,za,on. Her ongoing work explores how neuronal
adapta,ons drive allergic diseases.