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Caroline Sokol, MD, PhD

Caroline Sokol, MD, PhD

Caroline Sokol, MD, PhD is a physician-scien,st at Massachuse0s General Hospital and Assistant Professor of Medicine at Harvard Medical School. Her laboratory inves,gates neuroimmune circuits that govern allergen sensing, allergic immune ini,a,on and itch. Her research has demonstrated that sensory neurons are primary sensors of protease allergens and play a central role in ac,va,ng dendri,c cells and ini,a,ng allergic immunity. Her team also iden,fied a novel neuroimmune circuit in which IL-3-producing γc T cells prime IL-3 receptorexpressing sensory neurons to respond to minimal allergen exposure, linking microbial and environmental cues to allergic sensi,za,on. Her ongoing work explores how neuronal adapta,ons drive allergic diseases.